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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNB1
All Species:
33.94
Human Site:
T75
Identified Species:
57.44
UniProt:
P35222
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35222
NP_001091679.1
781
85497
T75
Q
G
F
S
Q
S
F
T
Q
E
Q
V
A
D
I
Chimpanzee
Pan troglodytes
XP_001137676
774
84747
D74
F
T
Q
E
Q
V
A
D
I
D
G
Q
Y
A
M
Rhesus Macaque
Macaca mulatta
XP_001115474
511
55731
Dog
Lupus familis
XP_850439
744
81740
L71
V
P
Q
S
Q
G
D
L
E
Y
Q
M
S
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q02248
781
85452
T75
Q
G
F
S
Q
S
F
T
Q
E
Q
V
A
D
I
Rat
Rattus norvegicus
Q9WU82
781
85436
T75
Q
G
F
S
Q
S
F
T
Q
E
Q
V
A
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516985
781
85506
T75
Q
G
F
S
Q
S
F
T
Q
E
Q
V
A
D
I
Chicken
Gallus gallus
NP_990412
781
85420
T75
Q
G
F
S
Q
S
F
T
Q
E
Q
V
A
D
I
Frog
Xenopus laevis
P26233
781
85431
T75
Q
G
F
S
Q
S
F
T
Q
D
Q
V
A
D
I
Zebra Danio
Brachydanio rerio
NP_571134
780
85502
N74
Q
G
F
N
Q
S
F
N
Q
E
Q
V
A
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18824
843
91134
T83
T
G
F
P
Q
N
F
T
Q
D
Q
V
D
D
M
Honey Bee
Apis mellifera
XP_391947
811
88602
T84
Q
G
F
A
Q
G
F
T
Q
D
Q
V
D
E
M
Nematode Worm
Caenorhab. elegans
O44326
678
74493
E70
V
M
D
L
L
T
Y
E
G
S
N
D
M
S
G
Sea Urchin
Strong. purpuratus
NP_001027543
825
89711
T96
A
G
Y
G
Q
A
Y
T
Q
E
Q
V
D
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
65.4
66.4
N.A.
99.8
99.7
N.A.
99.7
99.3
97.4
97.1
N.A.
65.7
67.6
28.5
67.2
Protein Similarity:
100
99
65.4
77.4
N.A.
99.8
99.7
N.A.
99.8
99.6
99
98.9
N.A.
77.2
80.1
46.4
77.7
P-Site Identity:
100
6.6
0
20
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
60
60
0
46.6
P-Site Similarity:
100
20
0
40
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
80
86.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
0
0
0
0
0
50
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
8
0
29
0
8
22
58
0
% D
% Glu:
0
0
0
8
0
0
0
8
8
50
0
0
0
15
0
% E
% Phe:
8
0
65
0
0
0
65
0
0
0
0
0
0
0
0
% F
% Gly:
0
72
0
8
0
15
0
0
8
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
50
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
29
% M
% Asn:
0
0
0
8
0
8
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
58
0
15
0
86
0
0
0
72
0
79
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
50
0
50
0
0
0
8
0
0
8
8
0
% S
% Thr:
8
8
0
0
0
8
0
65
0
0
0
0
0
8
8
% T
% Val:
15
0
0
0
0
8
0
0
0
0
0
72
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
15
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _